Multiple variants of African swine fever virus circulating in Vietnam

Tác giả : Van Tam Nguyen, Ki-hyun Cho, Nguyen Tuan Anh Mai, Jee-Yong Park, Thi Bich Ngoc Trinh, Min-Kyung Jang, Thi Thu Huyen Nguyen, Xuan Dang Vu, Thi Lan Nguyen, Van Diep Nguyen, Aruna Ambagala, Yong-Joo Kim, Van Phan Le

Thuộc tạp chí : Tạp chí Khoa học kỹ thuật chăn nuôi

Số : 167(4)

Tạp chí thuộc : Tạp chí quốc tế khác

Năm xuất bản : 2021

Nước xuất bản : Úc

Tóm tắt :

African swine fever (ASF) is a contagious and deadly viral disease affecting swine of all ages. ASF was first reported in
Vietnam in February 2019, and it is now considered endemic in Vietnam. In this study, 122 ASF-positive samples collected
from domestic pigs in 28 different provinces of northern, central, and southern Vietnam during outbreaks in 2019–2021 were
genetically characterized. The findings confirmed that all ASF virus (ASFV) strains circulating in Vietnam belonged to p72
genotype II, p54 genotype II, CD2v serogroup 8, and CVR gene variant type I. However, further analysis based on the tandem
repeat sequences located between I73R and I329L genes revealed that there were three different variants of ASFV, IGR I, II,
and III, circulating in the domestic pig population in Vietnam. The IGR II variants were the most prevalent (117/122 strains)
and were detected in pigs in all of the provinces tested, followed by IGR III (4/122 strains) and IGR I (1/122 strains). This
study confirms for the first time the presence of IGR III variants in Vietnam.